ZIPSOR® (diclofenac potassium) is a prescription Non-Steroidal Anti-Inflammatory Drug (NSAID). ZIPSOR is used for relief of mild-to-moderate pain in adults (18 years of age and older).
About ZIPSOR, a non-opioid approach
World Health Organization (WHO) recommendations for acute pain1
The US government’s Centers for Disease Control and Prevention (CDC) recommends that2:
NSAIDs have been used for pain for nearly 60 years and are widely prescribed and recommended by physicians.
ProSorb® technology maximizes absorption3
ZIPSOR is designed for rapid, consistent absorption3*
*Study conducted in healthy volunteers ≥ 18 years of age.
Significant pain reduction with every dose6,7
Primary endpoint: pain reduction over 48 hours after bunionectomy6,7
Bunionectomy surgery results in considerable pain and is a standard model for assessing efficacy of an acute pain medication.8
Study Design: This Phase III, randomized, double-blind, parallel-group, placebo-controlled study was conducted in a single-dose period and a multiple-dose period. Patients with a qualifying level of postsurgical pain (score ≥4 on an 11-point NPRS from 0=no pain to 10=worst possible pain) were randomly assigned to receive ZIPSOR 25 mg or placebo soft gelatin capsules in a 1:1 ratio.7
Use of rescue medication (1-2 hydrocodone/acetaminophen tablets) during the inpatient 48-hour multiple-dose period after bunionectomy in patients who received ZIPSOR 25 mg or placebo. Day 3 was not a full day, and the data reflect use of rescue medication only up to the time of discharge.7