ZIPSOR® (diclofenac potassium) is a prescription Non-Steroidal Anti-Inflammatory Drug (NSAID). ZIPSOR is used for relief of mild-to-moderate pain in adults (18 years of age and older).

What is ZIPSOR?

ZIPSOR is a prescription treatment for mild-to-moderate acute pain in adults 18 years of age or older.

The most common side effects of ZIPSOR include abdominal pain, constipation, diarrhea, dyspepsia, nausea, and vomiting; also reported were dizziness, headache, somnolence, pruritus, and increased sweating.

Why is ZIPSOR prescribed?

ZIPSOR is prescribed for different types of pain, including after surgery or for an injury such as a sprain or strain.

How do I know if ZIPSOR is right for me?

  • Your pain is acute—most acute pain lasts less than 6 months and goes away when the underlying problem has healed
  • You prefer not to take an opioid
  • Your pain is mild to moderate—which means that you would probably rate it no higher than a 7 on a scale of 0 to 10

Why an NSAID?

The US government’s Centers for Disease Control and Prevention (CDC) recommends that1:

  • Acute mild-to-moderate pain may be managed without opioids
  • Non-opioid options include NSAIDs
  • You should ask your doctor about ways to relieve your pain that do not involve prescription opioids

NSAIDs have been used for pain for nearly 60 years and are widely prescribed and recommended by physicians.


ZIPSOR is designed for rapid and consistent absorption in your body with technology called ProSorb®.2

The technology helps the medicine quickly distribute in your stomach, so it can be rapidly absorbed in your body.3

ZIPSOR was studied in a clinical trial comparing ZIPSOR to placebo for patients who underwent bunionectomy surgery, which is the removal of a bony deformity on the foot.4


Download a copay card to save on ZIPSOR

You could save money on ZIPSOR by downloading a copay card.*

*Terms and conditions may apply. View savings card for full terms and conditions.

Please see Important Safety Information and full Prescribing Information, including BOXED WARNING.